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 การประชุมวิชาการ3D-Structure prediction, binding sites and expression analysis of ribosome inactivating proteins in Jatropha curcasผู้แต่ง: Danulada Pantharaj,  Dr.Kiattawee Choowongkomon, Associate Professor , Dr.Sunanta Ratanapo, Associate Professor , Dr.Piyada Juntawong, Associate Professor , Dr.Chotika Yokthongwattana, Associate Professor , การประชุมวิชาการ:  
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 หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : 3D Structure of the Juxtamembrane Domain of the Human Epidermal Growth Factor Receptor and Its Interaction with Calmodulin by NMR Spectroscopy) ผู้เขียน:ดร.เกียรติทวี ชูวงศ์โกมล, รองศาสตราจารย์, Cathleen Carlin, Frank D. S?nnichsen สื่อสิ่งพิมพ์:pdf AbstractEpidermal growth factor receptor (EGFR) is involved in the regulation of cellular proliferation and differentiation. Its juxtamembrane domain (JX), plays important roles in receptor trafficking since both basolateral sorting in polarized epithelial cells and lysosomal sorting signals are identified in this region. In order to understand the regulation of these signals, we characterized the structural properties of recombinant JX domain in dodecylphosphocholine detergent (DPC) by nuclear magnetic resonance (NMR) spectroscopy. In DPC micelles, structures derived from NMR data showed three amphipathic, helical segments. Furthermore, JX domain showed to interact with calmodulin by NMR techniques. Two binding sites of calmodulin on JX domains were identified. Our data suggested that the activity of sorting signals may be regulated by their membrane association and calmodulin binding which imply the restricted accessibility in the intact receptor. |
ผลงานตีพิมพ์ในวารสารวิชาการMolecular cloning of kman coding for mannanase from Klebsiella oxytoca KUB-CW2-3 and its hybrid mannanase charactersผู้แต่ง:Pongsapipatana, N., Damrongteerapap, P., Chantorn, S., Dr.wilawan Sintuprapa, Lecturer , Dr.Suttipun Keawsompong, Associate Professor , Dr.Sunee Nitisinprasert, Associate Professor , วารสาร: 
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